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Pregnyl (HCG)

Pregnyl (HCG)

 HCG injection (Lyophilized) (Pregnyl®) is a medication that may assist with fertility treatments. It contains human chorionic gonadotropin (HCG), a hormone produced during pregnancy. Luteinizing hormone (LH), also produced by the body, supports egg development and stimulates ovulation before pregnancy. HCG has similar actions to LH, and when used for infertility, it mimics the LH surge to help stimulate ovulation. In women, HCG injections may be used to trigger ovulation and assist with infertility. In men, HCG may help increase sperm count in the treatment of certain types of hypogonadism. The timing and dosage of HCG injections in women are typically coordinated with other fertility treatments, such as follicle-stimulating hormone (FSH) therapy, to maximize the chances of conception. Pregnyl® may also help with assisted reproductive technologies like in vitro fertilization (IVF). Proper administration and adherence to the prescribed regimen are essential for achieving the desired outcomes in fertility treatments.
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How It Works

  • Human chorionic gonadotropin (HCG) is given as an injection under the skin or into a muscle. If you use this medicine at home, your doctor, nurse, or pharmacist will give you specific instructions on how and where to inject this medicine. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes. Do not use the medication if it has changed colors or the liquid has any particles in it.

Medication Information

Stop using HCG and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these signs of a blood clot: pain, warmth, redness, numbness, or tingling in your arm or leg; confusion, extreme dizziness, or severe headache.

Some women using this medicine have developed a condition called ovarian hyperstimulation syndrome (OHSS), especially after the first treatment cycle. OHSS can be a life-threatening condition.

Call your doctor right away if you have any of the following symptoms of OHSS: severe pelvic pain; swelling of the hands or legs; stomach pain and swelling; shortness of breath; weight gain; diarrhea; nausea or vomiting; or urinating less than normal. Follow your doctor’s instructions about any special care you may need during your pregnancy.

 Store dry powder at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Once reconstituted keep this medicine in a refrigerator between 36°F to 46°F (2°C to 8°C). Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain. 

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